Self-assessment questions: The acute porphyrias
Which of the following are potential precipitants of an attack of acute porphyria?
Cimetidine
Hormone replacement therapy
Pregnancy
Progesterone-only pill
Menopause
Which of the following are characteristic symptoms of an acute attack of porphyria?
Bipolar depression
Motor neuropathy
Sensory neuropathy
Leg pain
Hyponatraemia
Which of the following statements about haem are true?
Haem is essential for every cell in the body
Dietary haem intake from red meat reduces the rate of hepatic haem synthesis
Most haem is synthesised in the erythron
Haem deficiency explains most of the symptoms of acute porphyria
The rate of hepatic haem synthesis is increased in acute intermittent porphyria
Which of the following are useful in treating variegate porphyria?
Intravenous 5% dextrose
Gonadotrophin-releasing hormone agonists
Phenytoin
Liver transplantation
Opaque sun screen
Answers to these self-assessment questions can be found on page s92.
- © 2012 Royal College of Physicians
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