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Nephrogenic diabetes insipidus partially responsive to oral desmopressin in a subject with lithium-induced multiple endocrinopathy

C Kamath, J Govindan, AD Premawardhana, SJ Wood, MA Adlan and LD Premawardhana
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DOI: https://doi.org/10.7861/clinmedicine.13-4-407
Clin Med August 2013
C Kamath
1Section of Diabetes and Endocrinology, Department of Medicine, Caerphilly Miners’ and YYF Hospitals, Hengoed, Wales, UK
Roles: specialist registrar
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J Govindan
1Section of Diabetes and Endocrinology, Department of Medicine, Caerphilly Miners’ and YYF Hospitals, Hengoed, Wales, UK
Roles: specialist registrar
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AD Premawardhana
1Section of Diabetes and Endocrinology, Department of Medicine, Caerphilly Miners’ and YYF Hospitals, Hengoed, Wales, UK
Roles: foundation year doctor
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SJ Wood
1Section of Diabetes and Endocrinology, Department of Medicine, Caerphilly Miners’ and YYF Hospitals, Hengoed, Wales, UK
Roles: foundation year doctor
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MA Adlan
1Section of Diabetes and Endocrinology, Department of Medicine, Caerphilly Miners’ and YYF Hospitals, Hengoed, Wales, UK
Roles: consultant physician
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LD Premawardhana
1Section of Diabetes and Endocrinology, Department of Medicine, Caerphilly Miners’ and YYF Hospitals, Hengoed, Wales, UK
2University Hospital of Wales, Cardiff, UK
Roles: consultant physician
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    Fig 1.

    Radioactive iodine uptake scan showing very low thyroid uptake. Thryoid uptake here is 0.5% (a normal range would be 5–35%). Low RAI uptake and hyperthyroidism were indicative of Li-induced ‘destructive thyroiditis’. Li = lithium; RAI = radioactive iodine.

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    Fig 2.

    Abdominal CT scans showing bilateral dilated pelvicalyceal systems and hydroureters. Abdominal CT scans show dilated pelvicalyceal systems (a) and hydroureters (b) bilaterally. These are non-obstructive and occur due to large volume of renal and ureteric urine flow. CT = computed tomography.

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Nephrogenic diabetes insipidus partially responsive to oral desmopressin in a subject with lithium-induced multiple endocrinopathy
C Kamath, J Govindan, AD Premawardhana, SJ Wood, MA Adlan, LD Premawardhana
Clinical Medicine Aug 2013, 13 (4) 407-410; DOI: 10.7861/clinmedicine.13-4-407

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Nephrogenic diabetes insipidus partially responsive to oral desmopressin in a subject with lithium-induced multiple endocrinopathy
C Kamath, J Govindan, AD Premawardhana, SJ Wood, MA Adlan, LD Premawardhana
Clinical Medicine Aug 2013, 13 (4) 407-410; DOI: 10.7861/clinmedicine.13-4-407
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