Host genetic factors in susceptibility to mycobacterial disease
Christopher JA Duncan and Sophie Hambleton
DOI: https://doi.org/10.7861/clinmedicine.14-6-s17
Clin Med December 2014 Christopher JA Duncan
AInstitute of Cellular Medicine, Newcastle University, Newcastle-upon-Tyne, UK, and Great North Children's Hospital, Newcastle-upon-Tyne, UK
Roles: professor of paediatrics and immunology, and honorary consultant paediatrician
Sophie Hambleton
BInstitute of Cellular Medicine, Newcastle University, Newcastle-upon-Tyne, UK, and Department of Infection and Tropical Medicine Royal Victoria Infirmary, Newcastle-upon-Tyne, UK
Roles: academic clinical lecturer in infectious diseases
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Host genetic factors in susceptibility to mycobacterial disease
Christopher JA Duncan, Sophie Hambleton
Clinical Medicine Dec 2014, 14 (Suppl 6) s17-s21; DOI: 10.7861/clinmedicine.14-6-s17
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- ABSTRACT
- Mycobacterial disease
- Mycobacterial pathogenesis
- Mycobacterial susceptibility
- Aims and scope
- Single gene factors in mycobacterial disease susceptibility
- DC deficiency in mycobacterial susceptibility
- DC development in humans
- DC deficiency
- DCML because of GATA2 mutation
- DC deficiency resulting from IRF8 mutations
- Perspectives on DC development and function
- Summary
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