Iatrogenic Cushing’s syndrome due to drug interaction between glucocorticoids and the ritonavir or cobicistat containing HIV therapies
Emilie R Elliot, Aikaterini Theodoraki, Lakshmi R Jain, Neal J Marshall, Marta Boffito, Stephanie E Baldeweg and Laura J Waters
DOI: https://doi.org/10.7861/clinmedicine.16-5-412
Clin Med October 2016 Emilie R Elliot
AChelsea and Westminster Hospital, London, UK
Roles: specialty registrar in HIV/genito-urinary medicine
Aikaterini Theodoraki
BUniversity College London Hospitals Foundation Trust, London, UK
Roles: specialty registrar in endocrinology
Lakshmi R Jain
CMortimer Market Centre, London, UK
Roles: specialty registrar in GUM/HIV
Neal J Marshall
DIan Charleson Centre for HIV Medicine, Royal Free London NHS Foundation Trust, London, UK
Roles: specialty pharmacist in HIV
Marta Boffito
EChelsea and Westminster Hospital, London, UK
Roles: HIV consultant physician
Stephanie E Baldeweg
FUniversity College London Hospitals Foundation Trust, London, UK
Roles: consultant physician in diabetes and endocrinology
Laura J Waters
GMortimer Market Centre, London, UK
Roles: HIV consultant physician
Article Information
vol. 16 no. 5 412-418
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History:
- Published online October 3, 2016.
Copyright & Usage:
© Royal College of Physicians 2016. All rights reserved.
Author Information
- Emilie R Elliot, specialty registrar in HIV/genito-urinary medicineA⇑,
- Aikaterini Theodoraki, specialty registrar in endocrinologyB,
- Lakshmi R Jain, specialty registrar in GUM/HIVC,
- Neal J Marshall, specialty pharmacist in HIVD,
- Marta Boffito, HIV consultant physicianE,
- Stephanie E Baldeweg, consultant physician in diabetes and endocrinologyF and
- Laura J Waters, HIV consultant physicianG
- AChelsea and Westminster Hospital, London, UK
- BUniversity College London Hospitals Foundation Trust, London, UK
- CMortimer Market Centre, London, UK
- DIan Charleson Centre for HIV Medicine, Royal Free London NHS Foundation Trust, London, UK
- EChelsea and Westminster Hospital, London, UK
- FUniversity College London Hospitals Foundation Trust, London, UK
- GMortimer Market Centre, London, UK
- Address for correspondence: Dr E R Elliot, 369 Fulham Road, London SW10 9NH, UK. Email: emilieelliot{at}doctors.net.uk
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Iatrogenic Cushing’s syndrome due to drug interaction between glucocorticoids and the ritonavir or cobicistat containing HIV therapies
Emilie R Elliot, Aikaterini Theodoraki, Lakshmi R Jain, Neal J Marshall, Marta Boffito, Stephanie E Baldeweg, Laura J Waters
Clinical Medicine Oct 2016, 16 (5) 412-418; DOI: 10.7861/clinmedicine.16-5-412
Citation Manager Formats
Iatrogenic Cushing’s syndrome due to drug interaction between glucocorticoids and the ritonavir or cobicistat containing HIV therapies
Emilie R Elliot, Aikaterini Theodoraki, Lakshmi R Jain, Neal J Marshall, Marta Boffito, Stephanie E Baldeweg, Laura J Waters
Clinical Medicine Oct 2016, 16 (5) 412-418; DOI: 10.7861/clinmedicine.16-5-412
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- Article
- ABSTRACT
- Introduction
- Methods
- Results
- Discussion
- Prevention of pharmacological interaction via safe prescribing in patients treated with CYP3A4 inhibitors
- Prevention of pharmacological interaction via integration and patient empowerment
- Investigation of ICS/SAI and management of high-risk co-prescription
- Treatment of patients with symptomatic SAI
- Limitations
- Conclusion
- Conflicts of interests
- Author contributions
- Supplementary material
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