Motor neuron disease: biomarker development for an expanding cerebral syndrome
Martin R Turner
DOI: https://doi.org/10.7861/clinmedicine.16-6-s60
Clin Med December 2016 Martin R Turner
AMedical Research Council senior clinical fellow, Nuffield Department of Clinical Neurosciences, University of Oxford, UK
Roles: professor of clinical neurology and neuroscience
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Motor neuron disease: biomarker development for an expanding cerebral syndrome
Martin R Turner
Clinical Medicine Dec 2016, 16 (Suppl 6) s60-s65; DOI: 10.7861/clinmedicine.16-6-s60
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- ABSTRACT
- Introduction
- An unmistakeable clinical syndrome
- The emergence of the anterior brain
- The expanding genetic and cellular complexity
- Clinical heterogeneity and the biomarker need
- Insights from neuroimaging
- Prospects for a neurochemical biomarker
- The pre-symptomatic landscape
- Looking ahead
- Conflicts of interest
- References
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