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James B Maurice and Pinelopi Manousou
DOI: https://doi.org/10.7861/clinmedicine.18-5-440
Clin Med October 2018 James B Maurice
AImperial College London, London, UK
Roles: Clinical research fellow
Pinelopi Manousou
BImperial College Healthcare NHS Trust, London, UK
Roles: Hepatology consultant
We thank the reader for their clarification and raising this important point. They are correct in highlighting the concerns about the side effects associated with the few available treatments for nonalcoholic steatohepatitis (NASH), of which prostate cancer with vitamin E is an important one. This explains the very limited uptake of these drugs currently in clinical practice, and only weak recommendations for their use in guidelines.1 There is an unmet need for safe and effective treatments for NASH, and the exciting developments with major phase III trials in this field will hopefully begin to address this in the near future.
- © Royal College of Physicians 2018. All rights reserved.
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- National Institute for Health and Care Excellence
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James B Maurice, Pinelopi Manousou
Clinical Medicine Oct 2018, 18 (5) 440; DOI: 10.7861/clinmedicine.18-5-440
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