CME Medical Masterclass (122612): self-assessment questionnaire
SAQs and answers are ONLINE for RCP fellows and collegiate members
Format
Candidates are asked to choose the best answer from the five possible answers. This best of five format is used in many medical examinations.
The answering process
Go to www.rcplondon.ac.uk/SAQ
Log on using your usual RCP username and password
Select the relevant CME question paper
Answer all 10 questions by selecting the best answer from the options provided
Once you have answered all the questions, click on Submit
Registering your external CPD credits
Carrying out this activity allows you to claim two external CPD credits. These will be automatically transferred to your CPD diary, where you can review the activity and claim your points.
A 68-year-old woman presented with bone pain and was found to have renal impairment. Further investigation established a diagnosis of myeloma.Which factors are used to determine the stage of myeloma in the International Staging System?
Albumin and β2-microglobulin
β2-microglobulin and creatinine
Calcium and creatinine
Calcium and haemoglobin
Haemoglobin and albumin
A 72-year-old man presented with general malaise and breathlessness. He was found to have anaemia and hypercalcaemia, and a diagnosis of myeloma was made. He was treated with combination chemotherapy including lenalidomide.Which is the most important side effect of lenalidomide?
Gastrointestinal bleeding
Hepatitis
Pulmonary fibrosis
Skin rash
Thromboembolism
A 38-year-old asymptomatic woman was found to have an abnormal ECG on routine screening, with T wave inversion in the lateral leads. An echocardiogram revealed asymmetric septal hypertrophy with systolic anterior motion of the mitral valve, but there was no significant left ventricular outflow tract obstruction. A 24-hour ECG recording was normal.What treatment does she require?
Amiodarone
Bisoprolol
Diltiazem
Implantable cardioverter-defibrillator
None
A 32-year-old man presented with exertional chest pain and palpitations. On examination he had a jerky pulse and an ejection systolic murmur that was heard widely over the praecordium. An echocardiogram showed appearances consistent with hypertrophic cardiomyopathy. He had three children and was concerned that they might have inherited the condition from him.What is the typical inheritance pattern of hypertrophic cardiomyopathy?
Autosomal dominant
Autosomal recessive
Mitochondrial
Polygenic
X-linked
A 34-year-old woman had bronchiectasis due to cystic fibrosis. In the past year she had suffered three acute chest infections requiring antibiotic treatment. She was now well, but culture of her sputum on two occasions 3 months apart revealed that she was colonised with Pseudomonas aeruginosa.What is the most appropriate treatment?
Intravenous ciprofloxacin
Intravenous tobramycin
Nebulised ciprofloxacin
Nebulised tobramycin
Oral ciprofloxacin
A 42-year-old man presented with a 6-month history of worsening cough, sputum production and breathlessness. Examination of the chest revealed bilateral coarse crackles. A diagnosis of allergic bronchopulmonary aspergillosis was established.Aside from oral steroid, which drug is indicated?
Amphotericin
Caspofungin
Fluconazole
Itraconazole
Voriconazole
A 28-year-old woman presented with paroxysmal attacks of sweating and tachycardia. A diagnosis of phaeochromocytoma was made. Her mother had also been diagnosed with phaeochromocytoma.Mutation in which gene is the most likely cause of her familial phaeochromocytoma?
Dopamine β-hydroxylase
Erythropoietin
Fumarate hydratase
Phenylethanolamine N-methyltransferase
Succinate dehydrogenase
A 56-year-old man presented with severe hypertension due to a phaeochromocytoma.
What is the most appropriate initial anti-hypertensive drug?
Amlodipine
Bisoprolol
Labetalol
Phenoxybenzamine
Propanolol
A 32-year-old woman presented with a diarrhoeal illness complicated by a microangiopathic haemolytic anaemia and acute kidney injury. A diagnosis of diarrhoea-associated haemolytic–uraemic syndrome (dHUS) was made.
What is the most likely infection to have caused this presentation?
Campylobacter jejuni
Escherichia coli
Giardia lamblia
Salmonella enteritidis
Staphylococcus aureus
A 28-year-old man presented with malaise and bleeding from his nose. Examination revealed petechiae and purpura. Laboratory investigation demonstrated anaemia, thrombocytopenia and acute kidney injury. A diagnosis of atypical haemolytic–uraemic syndrome (aHUS) was suspected, later confirmed by demonstration of an inherited defect in a protein that regulates complement activation.
What is the best treatment?
Adalimumab
Basiliximab
Eculizumab
Infliximab
Omalizumab
CME Neurology SAQ
Answers to the CME SAQ published in Clinical Medicine in October 2018
Q1 Q2 Q3 Q4 Q5 Q6 Q7 Q8 Q9 Q10
(c) (b) (c) (b) (b) (d) (c) (a) (c) (b)
- © Royal College of Physicians 2019. All rights reserved.
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