The role of complement in kidney disease
Jamie Willows, Matthew Brown and Neil S Sheerin
DOI: https://doi.org/10.7861/clinmed.2019-0452
Clin Med March 2020 Jamie Willows
AJames Cook University Hospital, Middlesbrough, UK
Roles: nephrology specialty trainee
Matthew Brown
BRoyal Victoria Infirmary, Newcastle upon Tyne, UK
Roles: anaesthetics specialty trainee
Neil S Sheerin
CFreeman Hospital, Newcastle upon Tyne, UK and Newcastle University, Newcastle upon Tyne, UK
Roles: professor of nephrology
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The role of complement in kidney disease
Jamie Willows, Matthew Brown, Neil S Sheerin
Clinical Medicine Mar 2020, 20 (2) 156-160; DOI: 10.7861/clinmed.2019-0452
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- ABSTRACT
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- Introduction
- Prototypical complement-mediated kidney diseases; atypical haemolytic uraemic syndrome and C3 glomerulopathy
- The broader spectrum of complement-mediated kidney disease
- Complement activation in kidney transplantation
- Therapeutic complement inhibition
- Conclusion
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