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Does regulating the sale of high-strength beer and cider impact hospital admissions with decompensated alcohol-related liver disease: A retrospective cohort study

Yazan Haddadin, Dev Katarey, Manavi Sachdeva, Laura Vickers, Ishleen Kaur, Ahmed Hashim and Sumita Verma
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DOI: https://doi.org/10.7861/clinmed.2019-0390
Clin Med May 2020
Yazan Haddadin
ABrighton and Sussex University Hospitals NHS Trust, Brighton, UK
Roles: core medical trainee
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  • For correspondence: yazan.haddadin@nhs.net
Dev Katarey
BBrighton and Sussex University Hospitals NHS Trust, Brighton, UK and Brighton and Sussex Medical School, Brighton, UK
Roles: academic specialist trainee
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Manavi Sachdeva
CBrighton and Sussex University Hospitals NHS Trust, Brighton, UK
Roles: foundation year trainee
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Laura Vickers
CBrighton and Sussex University Hospitals NHS Trust, Brighton, UK
Roles: foundation year trainee
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Ishleen Kaur
CBrighton and Sussex University Hospitals NHS Trust, Brighton, UK
Roles: foundation year trainee
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Ahmed Hashim
BBrighton and Sussex University Hospitals NHS Trust, Brighton, UK and Brighton and Sussex Medical School, Brighton, UK
Roles: academic specialist trainee
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Sumita Verma
DBrighton and Sussex University Hospitals NHS Trust, Brighton, UK
Roles: professor in hepatology
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    Fig 1.

    a) Prevalence of consumption of different types of alcohol in phases 1 and 2. * = statistically significant, p<0.05. b) Yearly trend in the choice of alcohol (as a percentage of patients admitted with alcohol-related liver disease) following introduction of Sensible on Strength initiative. SoS = Sensible on Strength.

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    Fig 2.

    Kaplan–Meier graph showing overall mortality during phase 1 and 2 admissions.

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    Table 1.

    Number of premises signed up to the Sensible on Strength scheme by year

    YearOfficial members of the SoS initiative, nUnofficial members of the SoS initiative also banning cheap high-strength drinks, nTotal (percentage of all premises), n (%)
    2013–1479079 (24.5)
    2014–151190119 (36.8)
    2015–1613123154 (47.7)
    2016–1715939198 (61.3)
    2018–1917848226 (70.0)
    2019–2019149240 (74.3)
    • SoS = Sensible on Strength.

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    Table 2.

    Multivariate analysis of baseline demographic and clinical variables associated with inpatient mortality following index hospitalisation with decompensated alcohol-related liver disease

    Odds ratio95% confidence intervalp value
    Age, years1.090.97–1.220.140
    Gender, male3.330.17–67.50.433
    Duration of alcohol intake, years1.040.97–1.120.336
    Child–Pugh score0.640.31–1.310.224
    MELD score1.251.03–1.510.025
    Presence of infection2.680.27–26.20.397
    ICU stay, days4.580.17–1260.369
    • ICU = intensive care unit; MELD = Model for End-stage Liver Disease.

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    • Supplementary material S1
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Does regulating the sale of high-strength beer and cider impact hospital admissions with decompensated alcohol-related liver disease: A retrospective cohort study
Yazan Haddadin, Dev Katarey, Manavi Sachdeva, Laura Vickers, Ishleen Kaur, Ahmed Hashim, Sumita Verma
Clinical Medicine May 2020, 20 (3) 308-312; DOI: 10.7861/clinmed.2019-0390

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Does regulating the sale of high-strength beer and cider impact hospital admissions with decompensated alcohol-related liver disease: A retrospective cohort study
Yazan Haddadin, Dev Katarey, Manavi Sachdeva, Laura Vickers, Ishleen Kaur, Ahmed Hashim, Sumita Verma
Clinical Medicine May 2020, 20 (3) 308-312; DOI: 10.7861/clinmed.2019-0390
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