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‘Tiger woman sign’ hypercalcaemia: a diagnostic challenge

Adam Muse, Matthew Cates, Patrick Rogers, Michael Evans and Jonathan Walker
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DOI: https://doi.org/10.7861/clinmed.2020-0878
Clin Med January 2021
Adam Muse
ARoyal Devon and Exeter NHS Foundation Trust, Exeter, UK
Roles: internal medicine trainee
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  • For correspondence: adam.muse@nhs.net
Matthew Cates
BRoyal Devon and Exeter NHS Foundation Trust, Exeter, UK
Roles: consultant rheumatologist
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Patrick Rogers
CRoyal Devon and Exeter NHS Foundation Trust, Exeter, UK
Roles: consultant radiologist
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Michael Evans
DRoyal Devon and Exeter NHS Foundation Trust, Exeter, UK
Roles: specialty doctor
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Jonathan Walker
ERoyal Devon and Exeter NHS Foundation Trust, Exeter, UK
Roles: consultant endocrinologist
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    Fig 1.

    A proposed approach to the initial investigation of hypercalcaemia. CT = computed tomography; FHH = familial hypocalciuric hypercalcaemia; CaSR = calcium sensing receptor; eGFR = estimated glomerular filtration rate; PTH = parathyroid hormone; TAP = thorax, abdomen and pelvis.

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    Fig 2.

    Positron emission tomography showing diffuse fluorodeoxyglucose uptake isolated to muscles. This pattern of uptake is characteristic of sarcoid myositis and coined as ‘tiger man sign’.

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‘Tiger woman sign’ hypercalcaemia: a diagnostic challenge
Adam Muse, Matthew Cates, Patrick Rogers, Michael Evans, Jonathan Walker
Clinical Medicine Jan 2021, 21 (1) 73-75; DOI: 10.7861/clinmed.2020-0878

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‘Tiger woman sign’ hypercalcaemia: a diagnostic challenge
Adam Muse, Matthew Cates, Patrick Rogers, Michael Evans, Jonathan Walker
Clinical Medicine Jan 2021, 21 (1) 73-75; DOI: 10.7861/clinmed.2020-0878
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