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Implementation and evaluation of a COVID-19 rapid follow-up service for patients discharged from the emergency department

Lucy CK Bell, Caitlin Norris-Grey, Akish Luintel, Gabriella Bidwell, David Lanham, Michael Marks, Tim Baruah, Luke O'Shea, Melissa Heightman and Sarah Logan the University College London Hospitals COVID response team
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DOI: https://doi.org/10.7861/clinmed.2020-0816
Clin Med January 2021
Lucy CK Bell
AHospital for Tropical Diseases, London, UK
*joint first authors
Roles: infectious diseases registrar
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Caitlin Norris-Grey
BHospital for Tropical Diseases, London, UK
*joint first authors
Roles: medical student
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Akish Luintel
AHospital for Tropical Diseases, London, UK
*joint first authors
Roles: infectious diseases registrar
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Gabriella Bidwell
AHospital for Tropical Diseases, London, UK
Roles: infectious diseases registrar
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David Lanham
CUniversity College Hospital, London, UK
Roles: acute medicine registrar
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Michael Marks
DHospital for Tropical Diseases, London, UK and London School of Hygiene & Tropical Medicine, London, UK
Roles: infectious diseases consultant
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Tim Baruah
EUniversity College Hospital, London, UK
Roles: emergency medicine consultant
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Luke O'Shea
FUniversity College Hospital, London, UK
Roles: director of innovation
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Melissa Heightman
GUniversity College Hospital, London, UK
Roles: respiratory medicine consultant
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Sarah Logan
HHospital for Tropical Diseases, London, UK
Roles: infectious diseases consultant
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  • For correspondence: sarah.logan4@nhs.net
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    Fig 1.

    Rapid remote follow-up pathway. CRP = C-reactive protein; ED = emergency department; HR = heart rate; RR = respiration rate.

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    Table 1.

    Pilot cohort: patient demographics and characteristics at emergency department presentation, 27 April – 3 June 2020

    DemographicsAll patients, n=192
    Age, years, median (IQR)43 (32–55)
    Female, n (%)96 (50.0)
    Never smoker, n (%)97 (50.5)
    HCW or recent healthcare exposure, n (%)45 (23.4)
    Lives alone, n (%)55 (28.6)
    Characteristics
    Day of illness, median (IQR)13 (3–28)
    Oxygen saturation, %, median (IQR)98 (97–99)
    Respiratory rate, breaths per minute, median (IQR)18 (17–19)
    C-reactive protein, mg/L, median (IQR)2.2 (0.7–11.0)
    Chest X-ray abnormality (any), n (%)43 (22.4)
    D-dimer, μg/L, median (IQR)a355 (210–585)
    CTPA positive for pulmonary embolismb2/22
    Swabbed for SARS-CoV-2 in ED, n (%)153 (79.69)
    • Missing data: smoking status (10), household status (10), C-reactive protein (16), oxygen saturation (6), respiratory rate (5) and day of illness (5). Twenty patients did not have chest X-rays at ED attendance.

    • ↵a D-dimer was checked in 80 patients (low risk 52; medium risk 22; high risk 6);

    • ↵b 22 patients had CTPAs (low risk 10; medium risk 9; high risk 3). CTPA = computed tomography pulmonary angiography; HCW = healthcare worker; IQR = interquartile range.

    • View popup
    Table 2.

    Cohort trajectories

    All patients, n=192Confirmed or probable COVID-19, n=83Unlikely or uncertain COVID-19, n=109
    Discharged with pulse oximeter, n (%)8 (4.2)6 (7.2)2 (1.8)
    Using own pulse oximeter, n (%)21 (10.9)17 (20.5)4 (3.7)
    Number of telephone encounters, median (range)1 (1–6)1 (1–6)1 (1–4)
    Planned reattendances, n (%)23 (12.0)18 (21.7)5 (4.6)
    Planned reattendances leading to admissions, n (%)5 (2.6)4 (4.8)1 (0.9)
    Unplanned reattendances, n (%)9 (4.7)6 (7.2)3 (2.8)
    Unplanned reattendances leading to admissions, n (%)2 (1.0)2 (2.4)0 (0.0)
    • ‘Planned reattendances’ refers to patients who were recalled for face-to-face assessment by the telephone clinic. ‘Unplanned reattendances’ refers to patients who reattended without prompting.

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    Table 3.

    Outcomes

    All patients, n=192Confirmed or probable COVID-19, n=83Unlikely or uncertain COVID-19, n=109
    Discharged back to GP, n (%)131 (68.2)35 (42.2)96 (88.1)
    Referred to respiratory COVID-19 follow-up clinic, n (%)44 (22.9)41 (49.4)3 (2.8)
    Referred to other secondary care clinic, n (%)17 (8.9)7 (8.4)10 (9.2)
    • View popup
    Table 4.

    Validation cohort characteristics and trajectories; emergency department attendances 1 September – 23 October 2020

    DemographicsAll patients, n=134COVID-19 positive, n=47COVID-19 negative or swab not done, n=87
    Age, median (IQR)41 (28–56)47 (29–60)37 (27–53)
    Female, n (%)68 (50.7)23 (48.9)45 (51.7)
    Characteristics at ED presentation
    Oxygen saturation, %, median (IQR)97.5 (96–99)96 (95.5–98)96 (96–98)
    C-reactive protein, mg/L, median (IQR)8.4 (1.3–25.4)11 (3.7–24.7)6.9 (0.6–25.6)
    Cohort trajectories
    Number of telephone encounters, median (range)1 (1–8)2 (1–8)1 (1–5)
    Total reattendances, n (%)12 (9.0)7 (14.6)5 (5.7)
    Planned reattendances, n (%)5 (3.7)3 (6.2)2 (2.3)
    Planned reattendances leading to admissions, n (%)2 (1.5)2 (1.3)–
    Unplanned reattendances, n (%)7 (5.2)a4 (8.3)b3 (3.4)
    Unplanned reattendances leading to admissions, n (%)3 (2.2)3 (6.2)–
    • Missing data: oxygen saturation (2) and C-reactive protein (12).

    • ↵a of which five had been uncontactable by the telephone clinic;

    • ↵b of which two had been uncontactable; ED = emergency department; IQR = interquartile range.

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Implementation and evaluation of a COVID-19 rapid follow-up service for patients discharged from the emergency department
Lucy CK Bell, Caitlin Norris-Grey, Akish Luintel, Gabriella Bidwell, David Lanham, Michael Marks, Tim Baruah, Luke O'Shea, Melissa Heightman, Sarah Logan
Clinical Medicine Jan 2021, 21 (1) e57-e62; DOI: 10.7861/clinmed.2020-0816

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Implementation and evaluation of a COVID-19 rapid follow-up service for patients discharged from the emergency department
Lucy CK Bell, Caitlin Norris-Grey, Akish Luintel, Gabriella Bidwell, David Lanham, Michael Marks, Tim Baruah, Luke O'Shea, Melissa Heightman, Sarah Logan
Clinical Medicine Jan 2021, 21 (1) e57-e62; DOI: 10.7861/clinmed.2020-0816
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