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Figures
- Fig 1.
The change of SARS-CoV-2 positive rate over time. The fall in culture positivity from the third day after the onset of LPV/r therapy is remarkable. At day 6 after LPV/r therapy was initiated, 68.42% of patients were virologically cured and 84.22% of patients were virologically cured at day 12.
Tables
- Table 1.
Clinical characteristics and outcomes of severe COVID-19 patients treated with lopinavir–ritonavir (LPV/r) within 12 days of onset of symptoms
Case No. Sex Age Category of oxygen support Comorbidity Symptom onset to LPV/r therapy (days) Course of LPV/r use (days) Clinical outcomes Hospitalisation time (days) 1 M 63 Non-invasive ventilation None 9 12 Discharge 44 2 M 32 High-flow oxygen Hepatitis B infection 9 7 Discharge 17 3 M 71 Non-invasive ventilation None 11 8 Death N/A 4 M 73 High-flow oxygen Rheumatoid arthritis 4 10 Discharge 15 5 M 55 High-flow oxygen Hypertension Haemorrhage 7 12 Discharge 42 6 M 67 High-flow oxygen None 6 10 Discharge 13 7 M 57 High-flow oxygen None 10 7 Discharge 45 8 M 77 High-flow oxygen Gout 12 12 Discharge 29 9 F 75 High-flow oxygen None 8 14 Discharge 22 10 F 57 Non-invasive ventilation Hypertension, diabetes 11 11 Discharge 39 11 M 46 High-flow oxygen Hypertension 12 10 Discharge 11 12 F 65 High-flow oxygen None 3 12 Discharge 17 13 M 33 High-flow oxygen None 11 15 Discharge 15 14 F 46 High-flow oxygen None 5 14 Discharge 17 15 M 61 High-flow oxygen Diabetes 11 9 Discharge 14 16 F 38 High-flow oxygen None 2 11 Discharge 13 17 F 57 High-flow oxygen None 5 17 Discharge 35 18 F 72 High-flow oxygen None 12 10 Discharge 27 19 M 42 High-flow oxygen Diabetes 9 12 Discharge 17
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Effectiveness of early treatment of lopinavir–ritonavir in patients with severe COVID-19: a case series
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