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Probiotics for atopic dermatitis

Nada Boutrid and Hakim Rahmoune
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DOI: https://doi.org/10.7861/clinmed.Let.21.4.8
Clin Med July 2021
Nada Boutrid
Setif-1 University, Setif, Algeria and University Hospital of Setif, Setif, Algeria
Roles: Associate professor of paediatrics
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Hakim Rahmoune
Setif-1 University, Setif, Algeria and University Hospital of Setif, Setif, Algeria
Roles: Assistant professor of paediatrics
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Editor – We read with great attention the holistic and exhaustive review by Plant and Ardern-Jones about atopic dermatitis.1 However, we think that the increasing use of probiotics in the prophylactic and curative management of this condition deserves more attention.

In fact, probiotics were increasingly used during the last 2 decades, notably in infants and children; and the cumulated evidence is now conclusive through several systematic reviews and meta-analyses.

Particularly, treatments with mixed-strain probiotics have greater prophylactic and curative effects to both lower the risk of atopic dermatitis and reduce symptoms in children.2

Interestingly, regarding the preventive effect of such probiotics, strong evidence-based proofs recently demonstrated that supplementation with probiotics in both the antenatal period (in pregnant mothers) and postnatal period (in breastfeeding mothers then in infants) was efficient to reduce the incidence of atopic dermatitis in infancy and childhood.3,4

The era of microbiome-targeting drugs is here, and probiotics ought to be considered as a powerful, adjunct, preventive and curative therapy; especially in the paediatric population.

  • © Royal College of Physicians 2021. All rights reserved.

References

  1. ↵
    1. Plant A
    , Ardern-Jones MR. Advances in atopic dermatitis. Clin Med 2021;21:177–81.
    OpenUrlAbstract/FREE Full Text
  2. ↵
    1. Jiang W
    , Ni B, Liu Z, et al. The role of probiotics in the prevention and treatment of atopic dermatitis in children: an updated systematic review and meta-analysis of randomized controlled trials. Pediatr Drugs 2020;22:535–49.
    OpenUrl
  3. ↵
    1. Amalia N
    , Orchard D, Francis KL, King E. Systematic review and meta-analysis on the use of probiotic supplementation in pregnant mother, breastfeeding mother and infant for the prevention of atopic dermatitis in children. Australas J Dermatol 2020;61:e158–73.
    OpenUrl
  4. ↵
    1. Li L
    , Han Z, Niu X, et al. Probiotic supplementation for prevention of atopic dermatitis in infants and children: a systematic review and meta-analysis. Am J Clin Dermatol 2019;20:367–77.
    OpenUrl
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Probiotics for atopic dermatitis
Nada Boutrid, Hakim Rahmoune
Clinical Medicine Jul 2021, 21 (4) e430; DOI: 10.7861/clinmed.Let.21.4.8

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Probiotics for atopic dermatitis
Nada Boutrid, Hakim Rahmoune
Clinical Medicine Jul 2021, 21 (4) e430; DOI: 10.7861/clinmed.Let.21.4.8
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