Secondary haemophagocytic lymphohistiocytosis in hospitalised COVID-19 patients as indicated by a modified HScore is infrequent and high scores do not associate with increased mortality
Michael R Ardern-Jones, Matt Stammers, Hang TT Phan, Florina Borca, Anastasia Koutalopoulou, Ying Teo, James Batchelor, Trevor Smith and Andrew S Duncombe
DOI: https://doi.org/10.7861/clinmed.2021-0053
Clin Med September 2021 Michael R Ardern-Jones
AUniversity of Southampton, Southampton UK, and consultant dermatologist, University Hospital Southampton NHS Foundation Trust, Southampton, UK
Roles: associate professor
Matt Stammers
BUniversity Hospital Southampton NHS Foundation Trust, Southampton, UK and visiting research fellow, University of Southampton, Southampton, UK
Roles: consultant gastroenterologist
Hang TT Phan
CUniversity of Southampton, Southampton, UK, and data science fellow, NIHR Southampton Biomedical Research Centre, University Hospital Southampton NHS Foundation Trust, Southampton, UK
Roles: data science lead
Florina Borca
DUniversity of Southampton, Southampton, UK, and data science fellow, NIHR Southampton Biomedical Research Centre, University Hospital Southampton NHS Foundation Trust, Southampton, UK
Roles: senior information analyst for research & development
Anastasia Koutalopoulou
EUniversity Hospitals Southampton NHS Foundation Trust, Southampton, UK
Roles: clinical fellow
Ying Teo
EUniversity Hospitals Southampton NHS Foundation Trust, Southampton, UK
Roles: clinical fellow
James Batchelor
FClinical Informatics Research Unit, University of Southampton, Southampton, UK, and senior investigator, NIHR Southampton Biomedical Research Centre, University Hospital Southampton NHS Foundation Trust, Southampton, UK
Roles: director
Trevor Smith
GUniversity Hospital Southampton NHS Foundation Trust, Southampton, UK
Roles: consultant gastroenterologist
Andrew S Duncombe
HUniversity Hospital Southampton NHS Foundation Trust, Southampton, UK
Roles: consultant haematologist
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vol. 21 no. 5 e543-e547
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- Published online September 10, 2021.
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© Royal College of Physicians 2021. All rights reserved.
Author Information
- Michael R Ardern-Jones, associate professorA⇑,
- Matt Stammers, consultant gastroenterologistB,
- Hang TT Phan, data science leadC,
- Florina Borca, senior information analyst for research & developmentD,
- Anastasia Koutalopoulou, clinical fellowE,
- Ying Teo, clinical fellowE,
- James Batchelor, directorF,
- Trevor Smith, consultant gastroenterologistG and
- Andrew S Duncombe, consultant haematologistH
- AUniversity of Southampton, Southampton UK, and consultant dermatologist, University Hospital Southampton NHS Foundation Trust, Southampton, UK
- BUniversity Hospital Southampton NHS Foundation Trust, Southampton, UK and visiting research fellow, University of Southampton, Southampton, UK
- CUniversity of Southampton, Southampton, UK, and data science fellow, NIHR Southampton Biomedical Research Centre, University Hospital Southampton NHS Foundation Trust, Southampton, UK
- DUniversity of Southampton, Southampton, UK, and data science fellow, NIHR Southampton Biomedical Research Centre, University Hospital Southampton NHS Foundation Trust, Southampton, UK
- EUniversity Hospitals Southampton NHS Foundation Trust, Southampton, UK
- FClinical Informatics Research Unit, University of Southampton, Southampton, UK, and senior investigator, NIHR Southampton Biomedical Research Centre, University Hospital Southampton NHS Foundation Trust, Southampton, UK
- GUniversity Hospital Southampton NHS Foundation Trust, Southampton, UK
- HUniversity Hospital Southampton NHS Foundation Trust, Southampton, UK
- Address for correspondence: Dr Michael R Ardern-Jones, Clinical Experimental Sciences, University of Southampton Faculty of Medicine, Mailpoint 825, Level F, South Block, Sir Henry Wellcome Laboratories, Southampton General Hospital, Southampton SO16 6YD, UK. Email: m.aj{at}soton.ac.uk Twitter: @MikeAJderm
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Secondary haemophagocytic lymphohistiocytosis in hospitalised COVID-19 patients as indicated by a modified HScore is infrequent and high scores do not associate with increased mortality
Michael R Ardern-Jones, Matt Stammers, Hang TT Phan, Florina Borca, Anastasia Koutalopoulou, Ying Teo, James Batchelor, Trevor Smith, Andrew S Duncombe
Clinical Medicine Sep 2021, 21 (5) e543-e547; DOI: 10.7861/clinmed.2021-0053
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Secondary haemophagocytic lymphohistiocytosis in hospitalised COVID-19 patients as indicated by a modified HScore is infrequent and high scores do not associate with increased mortality
Michael R Ardern-Jones, Matt Stammers, Hang TT Phan, Florina Borca, Anastasia Koutalopoulou, Ying Teo, James Batchelor, Trevor Smith, Andrew S Duncombe
Clinical Medicine Sep 2021, 21 (5) e543-e547; DOI: 10.7861/clinmed.2021-0053
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