Liver cells: biology to therapeutics
Humphrey Hodgson
DOI: https://doi.org/10.7861/clinmedicine.3-2-161
Clin Med March 2003 Humphrey Hodgson
Royal Free and University College Medical School, London

Abstract
The liver has a remarkable capacity to regenerate after injury. Recent work has demonstrated that repair may call upon either the division of pre-existing mature cells, or the expansion of intrahepatic progenitor cells. Furthermore, progenitors may migrate into the liver from the bone marrow. Understanding and exploiting the cell biology of the liver provides the basis for innovational treatment, including the use of growth factors, transplantation of isolated cells, genetic manipulation of hepatocytes and liver cell progenitors, and the development of artificial liver support systems.
- © 2003 Royal College of Physicians
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Liver cells: biology to therapeutics
Humphrey Hodgson
Clinical Medicine Mar 2003, 3 (2) 161-165; DOI: 10.7861/clinmedicine.3-2-161
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