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Brenner, the worm and the prize

Raymond Hoffenberg
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DOI: https://doi.org/10.7861/clinmedicine.3-3-285
Clin Med May 2003
Raymond Hoffenberg
Royal College of Physicians
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Abstract

The recent award of a Nobel Prize to Sydney Brenner crowns an astonishingly distinguished scientific career. He must have come very close to winning it several times in the past. A colleague described him as ‘a visionary who sees further into the future than anyone’. This is borne out by his decision - made 40 years ago - to study a one-millimetre long worm in detail to define the biochemical and genetic control of its development and differentiation. The impact of these studies has been so profound, with a significant bearing on human physiology and disease, that over 400 laboratories worldwide have now adopted the worm as a research tool. In this article, a brief outline is given of his work on the worm and of some of the highlights of his brilliant career.

  • Brenner
  • caenorhabditis elegans
  • development
  • differentiation
  • Nobel Prize
  • © 2003 Royal College of Physicians
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Brenner, the worm and the prize
Raymond Hoffenberg
Clinical Medicine May 2003, 3 (3) 285-286; DOI: 10.7861/clinmedicine.3-3-285

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Brenner, the worm and the prize
Raymond Hoffenberg
Clinical Medicine May 2003, 3 (3) 285-286; DOI: 10.7861/clinmedicine.3-3-285
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