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Severe acute respiratory syndrome (SARS): a review

Pandurangan Vijayanand, Ed Wilkins and Mark Woodhead
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DOI: https://doi.org/10.7861/clinmedicine.4-2-152
Clin Med March 2004
Pandurangan Vijayanand
∗Department of Respiratory Medicine, Manchester Royal Infirmary
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Ed Wilkins
Department of Infectious Diseases, North Manchester Geneal Hospital
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Mark Woodhead
∗Department of Respiratory Medicine, Manchester Royal Infirmary
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Abstract

Severe acute respiratory syndrome (SARS) is a newly emerged disease that rapidly spread around the world. The disease originated in southern China and a novel coronavirus (SARS CoV) has been implicated as the causative organism. The path this virus took to set up human infection remains a mystery, though preliminary data point to origins in an animal reservoir. Nosocomial transmission of SARS CoV has been a striking feature in this epidemic. The clinical illness is similar to many acute respiratory infections, although a large proportion of patients show a rapid deterioration with respiratory distress towards the end of the second week of illness. The management principles are broadly similar to treating any community acquired pneumonia but the infection control measures take a pivotal role. There is no proven antiviral agent against SARS CoV. The most remarkable feature about the SARS epidemic was the speed with which the global community acted in a coordinated way to control it.

  • community acquired pneumonia
  • coronavirus
  • epidemic
  • SARS
  • SARS CoV
  • severe acute respiratory syndrome
  • © 2004 Royal College of Physicians
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SARS: a review
Pandurangan Vijayanand, Ed Wilkins, Mark Woodhead
Clinical Medicine Mar 2004, 4 (2) 152-160; DOI: 10.7861/clinmedicine.4-2-152

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SARS: a review
Pandurangan Vijayanand, Ed Wilkins, Mark Woodhead
Clinical Medicine Mar 2004, 4 (2) 152-160; DOI: 10.7861/clinmedicine.4-2-152
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