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Non-alcoholic fatty liver disease: current concepts and management strategies

Chris P Day, Geoffrey Haydon and Chris P Day
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DOI: https://doi.org/10.7861/clinmedicine.6-1-19
Clin Med January 2006
Chris P Day
University of Birmingham and Honorary Consultant, Queen Elizabeth Hospital, Birmingham
Roles: Professor of Hepatology
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Geoffrey Haydon
Queen Elizabeth Hospital, Birmingham
Roles: Consultant Physican
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Chris P Day
University of Newcastle upon Tyne
Roles: Head of School of Clinical Medical Sciences
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Abstract

Non-alcoholic fatty liver disease (NAFLD), the liver manifestation of the metabolic syndrome, is now considered to be the commonest liver problem in the western world. This apparent ‘epidemic’, coupled with an accumulating body of evidence that a significant proportion of patients with NAFLD can progress to cirrhosis, liver failure and hepatocellular carcinoma (HCC), has - perhaps not surprisingly - led to an exponential growth in clinical and basic studies investigating all aspects of this hitherto largely ignored disease. The result is a vast increase in understanding of the natural history, clinical features and pathophysiology of NAFLD over the last five years which has now begun to inform the development of rational management strategies.

  • © 2006 Royal College of Physicians
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Non-alcoholic fatty liver disease: current concepts and management strategies
Chris P Day
Clinical Medicine Jan 2006, 6 (1) 19-25; DOI: 10.7861/clinmedicine.6-1-19

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Non-alcoholic fatty liver disease: current concepts and management strategies
Chris P Day
Clinical Medicine Jan 2006, 6 (1) 19-25; DOI: 10.7861/clinmedicine.6-1-19
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