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Cardiovascular disease – the silent killer in rheumatoid arthritis

Namita Kumar and David J Armstrong
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DOI: https://doi.org/10.7861/clinmedicine.8-4-384
Clin Med August 2008
Namita Kumar
University Hospital of North Durham, Durham
Roles: Consultant Physician and Rheumatologist
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David J Armstrong
University Hospital of North Durham, Durham
Roles: Consultant Rheumatologist
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Abstract

Rheumatoid arthritis (RA) is a multi-system disease with high rates of morbidity and mortality. In recent years, there has been increasing focus on the growing rates of cardiovascular disease (CVD) in RA, over and above expected levels allowing for ‘traditional’ risk factors. In this paper the impact of CVD in RA, the relative contributions of traditional risk factors and novel risk factors (including homocysteine, oxidised low-density lipoprotein, high-sensitivity C-reactive protein and leptin), and the need to address cardiovascular risk in the fight against premature death from coronary artery and stroke disease in RA are discussed.

KEY WORDS
  • C-reactive protein
  • cardiovascular disease
  • coronary artery disease
  • homocysteine
  • hyperlipidaemia
  • hypertension
  • rheumatoid arthritis
  • © 2008 Royal College of Physicians
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Cardiovascular disease – the silent killer in rheumatoid arthritis
Namita Kumar, David J Armstrong
Clinical Medicine Aug 2008, 8 (4) 384-387; DOI: 10.7861/clinmedicine.8-4-384

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Cardiovascular disease – the silent killer in rheumatoid arthritis
Namita Kumar, David J Armstrong
Clinical Medicine Aug 2008, 8 (4) 384-387; DOI: 10.7861/clinmedicine.8-4-384
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