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De Testimonio: on the evidence for decisions about the use of therapeutic interventions

Michael Rawlins
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DOI: https://doi.org/10.7861/clinmedicine.8-6-579
Clin Med December 2008
Michael Rawlins
National Institute for Health and Clinical Excellence, London; Emeritus Professor, University of Newcastle, Newcastle upon Tyne
Roles: Chairman
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Abstract

Decisions about the use of therapeutic interventions, whether for individuals or entire healthcare systems, should be based on the totality of the available evidence. The notion that evidence can be reliably or usefully placed in ‘hierarchies’ is illusory. Rather, decision makers need to exercise judgement about whether (and when) evidence gathered from experimental or observational sources is fit for purpose.

Key Words
  • case-control studies
  • hierarchies of evidence
  • historical controlled trials
  • randomised controlled trials
  • © 2008 Royal College of Physicians
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The evidence for decisions about the use of therapeutic interventions
Michael Rawlins
Clinical Medicine Dec 2008, 8 (6) 579-588; DOI: 10.7861/clinmedicine.8-6-579

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The evidence for decisions about the use of therapeutic interventions
Michael Rawlins
Clinical Medicine Dec 2008, 8 (6) 579-588; DOI: 10.7861/clinmedicine.8-6-579
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