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The impact of false positive COVID-19 results in an area of low prevalence

Brendan Healy, Azizah Khan, Huria Metezai, Ian Blyth and Hibo Asad
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DOI: https://doi.org/10.7861/clinmed.2020-0839
Clin Med November 2020
Brendan Healy
APublic Health Wales Microbiology, Cardiff, UK
Roles: consultant in microbiology and infectious diseases
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  • For correspondence: brendan.healy@wales.nhs.uk
Azizah Khan
BCardiff University, Cardiff, UK
Roles: year-5 medical student
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Huria Metezai
BCardiff University, Cardiff, UK
Roles: year-5 medical student
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Ian Blyth
CPublic Health Wales, Swansea, UK and Swansea Bay University Health Board, Swansea, UK
Roles: consultant in microbiology and infectious diseases
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Hibo Asad
DPublic Health Wales, Swansea, UK and Swansea Bay University Health Board, Swansea, UK
Roles: healthcare epidemiologist
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ABSTRACT

False negative results in COVID-19 testing are well recognised and frequently discussed. False positive results, while less common and less frequently discussed, still have several adverse implications, including potential exposure of a non-infected person to the virus in a cohorted area. Although false positive results are proportionally greater in low prevalence settings, the consequences are significant at all times and potentially of greater significance in high-prevalence settings. We evaluated COVID-19 results in one area during a period of low prevalence. The consequences of these results are discussed and implications for these results in both high and low prevalence settings are considered. We also provide recommendations to minimise the risk and impact of false-positive results.

KEYWORDS
  • COVID-19
  • false positive results
  • high prevalence
  • low prevalence
  • © Royal College of Physicians 2020. All rights reserved.
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The impact of false positive COVID-19 results in an area of low prevalence
Brendan Healy, Azizah Khan, Huria Metezai, Ian Blyth, Hibo Asad
Clinical Medicine Nov 2020, clinmed.2020-0839; DOI: 10.7861/clinmed.2020-0839

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The impact of false positive COVID-19 results in an area of low prevalence
Brendan Healy, Azizah Khan, Huria Metezai, Ian Blyth, Hibo Asad
Clinical Medicine Nov 2020, clinmed.2020-0839; DOI: 10.7861/clinmed.2020-0839
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