If it ain’t broke don’t fix it: Lack of review of antimicrobials in ‘well’ patients – time for a CRP change

Article Figures & Data

Table 1.

Logistic regression univariate analysis of the likelihood of 48-hour review depending on category of C-reactive protein test result

Category	48-hour review, n/total n	Odds ratio	95% confidence interval	p value
CRP >100 mg/L	37/53	1	n/a	n/a
CRP 21–100 mg/L	23/52	0.34	0.15–0.76	0.009
CRP ≤20 mg/L	13/26	0.43	0.16–1.14	0.089
No CRP test	1/8	0.06	0.07–0.54	0.012
Total	74/139	n/a	n/a	n/a

Table 2.

Comparison of C-reactive protein value against a 48 hour antibiotic review at sites 1 and 2 pre- and post-intervention

Category	Site 1 pre-intervention 48-hour review, n/total n	Site 1 post-intervention 48-hour review, n/total n	Improvement, %	Site 2 pre-intervention 48-hour review, n/total n	Site 2 post-intervention 48-hour review, n/total n	Improvement, %
CRP >100 mg/L	14/20	10/12	13	23/33	4/5	10
CRP 21–100 mg/L	9/23	9/12	36	14/29	9/12	27
CRP ≤20 mg/L	4/9	2/2	56	9/17	1/2	–3
No CRP test	0/1	0/0	n/a	1/7	1/1	86
Total	27/53	21/26	30	47/86	15/20	20