TY - JOUR T1 - What we know so far: COVID-19 current clinical knowledge and research JF - Clinical Medicine JO - Clin Med SP - 124 LP - 127 DO - 10.7861/clinmed.2019-coron VL - 20 IS - 2 AU - Mary A Lake Y1 - 2020/03/01 UR - http://www.rcpjournals.org/content/20/2/124.abstract N2 - In December 2019, health authorities in Wuhan, China, identified a cluster of pneumonia cases of unknown aetiology linked to the city's South China Seafood Market. Subsequent investigations revealed a novel coronavirus, SARS-CoV-2, as the causative agent now at the heart of a major outbreak. The rising case numbers have been accompanied by unprecedented public health action, including the wholesale isolation of Wuhan. Alongside this has been a robust scientific response, including early publication of the pathogen genome, and rapid development of highly specific diagnostics. This article will review the new knowledge of SARS-CoV-2 COVID-19 acute respiratory disease, and summarise its clinical features. ER -