RT Journal Article
SR Electronic
T1 National review of deaths among HIV-infected adults
JF Clinical Medicine
JO Clin Med
FD Royal College of Physicians
SP 250
OP 252
DO 10.7861/clinmedicine.8-3-250
VO 8
IS 3
A1 SB Lucas
A1 H Curtis
A1 MA Johnson
YR 2008
UL http://www.rcpjournals.org/content/8/3/250.abstract
AB This review describes patterns of mortality among adults infected with HIV in the UK and assesses the contributions of late diagnosis of HIV infection and non-HIV-related disease to such mortality. In total, 387 adults with HIV who died between 1 October 2004 and 30 September 2005 after receiving care at 90 clinical centres in the UK were reviewed. Causes of death and scenarios accounting for death were measured. Of the 387 deaths, 218 (56.3%) were readily attributable to infection with HIV. Only 123 (31.8%) deaths were considered not directly related to HIV. Late diagnosis of HIV accounted for 24.0% of all deaths and 35.2% of HIV-related deaths. Infection with HIV remains the main cause of mortality among infected patients in the era of highly active antiretroviral therapy. Late diagnosis of infection with HIV may be the largest potentially remediable factor for HIV-associated death.