PT - JOURNAL ARTICLE AU - Seng Wee Cheo AU - Qin Jian Low AU - Yee Ann Tan AU - Yuen Kang Chia TI - Images of the month: Intractable vomiting and neuromyelitis optica spectrum disorder AID - 10.7861/clinmed.2020-0019 DP - 2020 May 01 TA - Clinical Medicine PG - e20--e21 VI - 20 IP - 3 4099 - http://www.rcpjournals.org/content/20/3/e20.short 4100 - http://www.rcpjournals.org/content/20/3/e20.full SO - Clin Med2020 May 01; 20 AB - Neuromyelitis optica spectrum disorder (NMOSD) is a rare inflammatory disorder of the nervous system which can be potentially debilitating. Its prevalence is estimated to be around 0.5–10 per 100,000 population with predilection towards Asians and females. It can be diagnosed based on core clinical characteristics, serum aquaporin antibodies and neuroimaging features. It is important to pick up the diagnosis of NMOSD as the treatment is different from other demyelinating disease. Here, we illustrate a case of NMOSD presented with intractable vomiting.