RT Journal Article SR Electronic T1 Images of the month: Intractable vomiting and neuromyelitis optica spectrum disorder JF Clinical Medicine JO Clin Med FD Royal College of Physicians SP e20 OP e21 DO 10.7861/clinmed.2020-0019 VO 20 IS 3 A1 Seng Wee Cheo A1 Qin Jian Low A1 Yee Ann Tan A1 Yuen Kang Chia YR 2020 UL http://www.rcpjournals.org/content/20/3/e20.abstract AB Neuromyelitis optica spectrum disorder (NMOSD) is a rare inflammatory disorder of the nervous system which can be potentially debilitating. Its prevalence is estimated to be around 0.5–10 per 100,000 population with predilection towards Asians and females. It can be diagnosed based on core clinical characteristics, serum aquaporin antibodies and neuroimaging features. It is important to pick up the diagnosis of NMOSD as the treatment is different from other demyelinating disease. Here, we illustrate a case of NMOSD presented with intractable vomiting.