PT  - JOURNAL ARTICLE
AU  - Jagan Murugachandran
AU  - David Gannon
TI  - Lessons of the month 2: McKittrick–Wheelock syndrome: Case report of a patient declining resection of a large villous adenoma
AID  - 10.7861/clinmed.2019-0356
DP  - 2020 May 01
TA  - Clinical Medicine
PG  - 295--297
VI  - 20
IP  - 3
4099  - http://www.rcpjournals.org/content/20/3/295.short
4100  - http://www.rcpjournals.org/content/20/3/295.full
SO  - Clin Med2020 May 01; 20
AB  - McKittrick–Wheelock syndrome (MWS) is a rare cause of acute kidney injury and electrolyte depletion. It is driven by a secretory tumour or polyp of the distal large colon. Although rare, it is a diagnosis that must be considered in patients presenting with the above conditions. Treatment is with surgical resection of the offending growth. We present the case of a 70-year-old woman who presented multiple times with electrolyte depletion and acute kidney injury. The diagnosis of MWS was established and treatment options discussed. Surgical intervention was declined, and management consisted of patient education, the careful replacement of fluid and electrolytes and close monitoring of electrolytes and kidney function. After a short period as an inpatient, the patient went on to be discharged and, with regular follow-up, has managed to continue a normal life.