PT - JOURNAL ARTICLE AU - Ahmed Hussain AU - Preya J Patel AU - Freya Rhodes AU - Ankur Srivastava AU - David Patch AU - William Rosenberg TI - Decompensated cirrhosis is the commonest presentation for NAFLD patients undergoing liver transplant assessment AID - 10.7861/clinmed.2019-0250 DP - 2020 May 01 TA - Clinical Medicine PG - 313--318 VI - 20 IP - 3 4099 - http://www.rcpjournals.org/content/20/3/313.short 4100 - http://www.rcpjournals.org/content/20/3/313.full SO - Clin Med2020 May 01; 20 AB - Non-alcoholic fatty liver disease (NAFLD) accounts for 10–15% of orthotopic liver transplants (OLTs) in the UK. Index presentations with cirrhotic decompensation represent missed opportunities for preventive treatment leaving OLT or palliation as the only options.We retrospectively reviewed patient records for all NAFLD patients undergoing assessment for OLT between January 2003 and December 2017.Data were available for 81 patients with NAFLD as the primary diagnosis. Fifty-two patients had decompensated cirrhosis at first presentation; 91.7% presented to secondary care compared to 52.7% referred from primary care (p=0.001). Cirrhosis was not suspected at the time of referral to hospital in 24.7% of patients subsequently assessed for OLT. Most patients undergoing assessment for OLT for NAFLD had decompensated cirrhosis at their first diagnosis of chronic liver disease. These data highlight the plight of patients with NAFLD cirrhosis in whom chronic liver disease is diagnosed late.