TY - JOUR T1 - SARS-CoV-2 serology: Test, test, test, but interpret with caution! JF - Clinical Medicine JO - Clin Med DO - 10.7861/clinmed.2020-0170 SP - clinmed.2020-0170 AU - William H Bermingham AU - Thomas Wilding AU - Sarah Beck AU - Aarnoud Huissoon Y1 - 2020/06/02 UR - http://www.rcpjournals.org/content/early/2020/06/11/clinmed.2020-0170.abstract N2 - SARS-CoV-2 serological tests are a subject of intense interest and have the potential to significantly enhance the diagnostic capability of healthcare services in the current pandemic. However, as with all novel assays, significant validation is required to understand the clinical relevance of results.We present the first study to assess clinician interpretation of SARS-CoV-2 serology scenarios. We identify common key assumptions regarding patient infectivity and protection that are not currently supported by the SARS-CoV-2 evidence base. In this rapidly developing field, we therefore strongly recommend serological assay results are accompanied by clear interpretive support from laboratory and infectious diseases specialists. ER -