PT  - JOURNAL ARTICLE
AU  - Sam LF Lau
AU  - Fernand M-M Lai
AU  - Kai-Ming Chow
AU  - Cheuk-Chun Szeto
TI  - Images of the month: Crystalglobulin-induced nephropathy
AID  - 10.7861/clinmed.2020-0116
DP  - 2020 Jul 01
TA  - Clinical Medicine
PG  - e125--e126
VI  - 20
IP  - 4
4099  - http://www.rcpjournals.org/content/20/4/e125.short
4100  - http://www.rcpjournals.org/content/20/4/e125.full
SO  - Clin Med2020 Jul 01; 20
AB  - We report a patient with chronic diabetes and was referred for recent onset proteinuria. Light microscopy of the renal biopsy specimen showed mildly expanded mesangium with mesangial hypercellularity and segmental sclerosis, features compatible with diabetic glomerulosclerosis. However, crystalglobulin-induced nephropathy with crystal deposit was identified on electron microscopy. Renal biopsy is often performed for diabetic patients who present with proteinuria and light microscopy often shows features of diabetic glomerulosclerosis. Additional information may occasionally be revealed on electron microscopy, altering the subsequent plan of management.