PT - JOURNAL ARTICLE AU - Wenhao Li AU - William Alazawi TI - Non-alcoholic fatty liver disease AID - 10.7861/clinmed.2020-0696 DP - 2020 Sep 01 TA - Clinical Medicine PG - 509--512 VI - 20 IP - 5 4099 - http://www.rcpjournals.org/content/20/5/509.short 4100 - http://www.rcpjournals.org/content/20/5/509.full SO - Clin Med2020 Sep 01; 20 AB - Non-alcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver disease worldwide. NAFLD is defined by excess fat in the liver and has a multidirectional relationship with metabolic syndrome. The prevalence of NAFLD has risen rapidly in recent years in line with the obesity epidemic and associated increases in type 2 diabetes, hypertension and hypercholesterolaemia. Patients with NAFLD are at risk of cardiovascular disease and cancer, and in a proportion of individuals, NAFLD is associated with liver damage. This article summarises the epidemiology of NAFLD, the clinical approach to risk-assessing patients and briefly outlines current and future management options.