PT - JOURNAL ARTICLE AU - Gautham Appanna AU - Yiannis Kallis TI - An update on the management of cholestatic liver diseases AID - 10.7861/clinmed.2020-0697 DP - 2020 Sep 01 TA - Clinical Medicine PG - 513--516 VI - 20 IP - 5 4099 - http://www.rcpjournals.org/content/20/5/513.short 4100 - http://www.rcpjournals.org/content/20/5/513.full SO - Clin Med2020 Sep 01; 20 AB - Cholestatic liver diseases are a challenging spectrum of conditions arising from damage to bile ducts, leading to build-up of bile acids and inflammatory processes that cause injury to cholangiocytes and hepatocytes. Primary biliary cholangitis (PBC) and primary sclerosing cholangitis (PSC) are the two most common cholestatic disorders. In this review we detail the latest guidelines for the diagnosis and management of patients with these two conditions.