TY - JOUR T1 - An update on the management of cholestatic liver diseases JF - Clinical Medicine JO - Clin Med SP - 513 LP - 516 DO - 10.7861/clinmed.2020-0697 VL - 20 IS - 5 AU - Gautham Appanna AU - Yiannis Kallis Y1 - 2020/09/01 UR - http://www.rcpjournals.org/content/20/5/513.abstract N2 - Cholestatic liver diseases are a challenging spectrum of conditions arising from damage to bile ducts, leading to build-up of bile acids and inflammatory processes that cause injury to cholangiocytes and hepatocytes. Primary biliary cholangitis (PBC) and primary sclerosing cholangitis (PSC) are the two most common cholestatic disorders. In this review we detail the latest guidelines for the diagnosis and management of patients with these two conditions. ER -