PT - JOURNAL ARTICLE AU - Sanjoy Ray AU - Shakeel A Qureshi AU - Natalie Stolagiewicz AU - Lydia Sturridge AU - Sitara Khan TI - An unusual case of persisting hypoxia in a patient with a thrombolysed pulmonary embolism AID - 10.7861/clinmed.2020-0753 DP - 2020 Nov 01 TA - Clinical Medicine PG - 593--596 VI - 20 IP - 6 4099 - http://www.rcpjournals.org/content/20/6/593.short 4100 - http://www.rcpjournals.org/content/20/6/593.full SO - Clin Med2020 Nov 01; 20 AB - Exertional breathlessness and hypoxia are common presenting complaints in acute medicine. We describe a case where the patient continued to have persistent hypoxia even after the primary cause (pulmonary embolism) was diagnosed and treated. The hypoxia persisted as an enigma, its cause remaining elusive till diagnosed. Standard first-line investigations would not have reached the underlying diagnosis in this case and, as such, it demonstrates the keen clinical sense and complex investigative strategy required to solve the puzzle.