TY - JOUR T1 - Long-term outcomes of liver transplant recipients followed up in non-transplant centres: Care closer to home JF - Clinical Medicine JO - Clin Med SP - e32 LP - e38 DO - 10.7861/clinmed.2020-0609 VL - 21 IS - 1 AU - Cynthia Tsien AU - Huey Tan AU - Sowmya Sharma AU - Naaventhan Palaniyappan AU - Pramudi Wijayasiri AU - Kristel Leung AU - Jatinder Hayre AU - Elizabeth Mowlem AU - Rachel Kang AU - Peter J Eddowes AU - Emilie Wilkes AU - Suresh V Venkatachalapathy AU - Indra N Guha AU - Lilia Antonova AU - Angela C Cheung AU - William JH Griffiths AU - Andrew J Butler AU - Stephen D Ryder AU - Martin W James AU - Guruprasad P Aithal AU - Aloysious D Aravinthan Y1 - 2021/01/01 UR - http://www.rcpjournals.org/content/21/1/e32.abstract N2 - Introduction Increasing rates of liver transplantation and improved outcomes have led to greater numbers of transplant recipients followed up in non-transplant centres. Our aim was to document long-term clinical outcomes of liver transplant recipients managed in this ‘hub-and-spoke’ healthcare model.Methods A retrospective analysis of all adult patients who underwent liver transplantation between 1987 and 2016, with post-transplant follow-up in two non-transplant centres in the UK (Nottingham) and Canada (Ottawa), was performed.Results The 1-, 5-, 10- and 20-year patient survival rates were 98%, 95%, 87% and 62%, and 100%, 96%, 88% and 62% in the Nottingham and Ottawa groups, respectively (p=0.87). There were no significant differences between the two centres in 1-, 5-, 10- and 20-year cumulative incidence of death-censored graft-survival (p=0.10), end-stage renal disease (p=0.29) or de novo cancer (p=0.22). Nottingham had a lower incidence of major cardiovascular events (p=0.008).Conclusion Adopting a new model of healthcare provides a means of delivering post-transplant patient care close to home without compromising patient survival and long-term clinical outcomes. ER -