PT - JOURNAL ARTICLE AU - Cynthia Tsien AU - Huey Tan AU - Sowmya Sharma AU - Naaventhan Palaniyappan AU - Pramudi Wijayasiri AU - Kristel Leung AU - Jatinder Hayre AU - Elizabeth Mowlem AU - Rachel Kang AU - Peter J Eddowes AU - Emilie Wilkes AU - Suresh V Venkatachalapathy AU - Indra N Guha AU - Lilia Antonova AU - Angela C Cheung AU - William JH Griffiths AU - Andrew J Butler AU - Stephen D Ryder AU - Martin W James AU - Guruprasad P Aithal AU - Aloysious D Aravinthan TI - Long-term outcomes of liver transplant recipients followed up in non-transplant centres: Care closer to home AID - 10.7861/clinmed.2020-0609 DP - 2021 Jan 01 TA - Clinical Medicine PG - e32--e38 VI - 21 IP - 1 4099 - http://www.rcpjournals.org/content/21/1/e32.short 4100 - http://www.rcpjournals.org/content/21/1/e32.full SO - Clin Med2021 Jan 01; 21 AB - Introduction Increasing rates of liver transplantation and improved outcomes have led to greater numbers of transplant recipients followed up in non-transplant centres. Our aim was to document long-term clinical outcomes of liver transplant recipients managed in this ‘hub-and-spoke’ healthcare model.Methods A retrospective analysis of all adult patients who underwent liver transplantation between 1987 and 2016, with post-transplant follow-up in two non-transplant centres in the UK (Nottingham) and Canada (Ottawa), was performed.Results The 1-, 5-, 10- and 20-year patient survival rates were 98%, 95%, 87% and 62%, and 100%, 96%, 88% and 62% in the Nottingham and Ottawa groups, respectively (p=0.87). There were no significant differences between the two centres in 1-, 5-, 10- and 20-year cumulative incidence of death-censored graft-survival (p=0.10), end-stage renal disease (p=0.29) or de novo cancer (p=0.22). Nottingham had a lower incidence of major cardiovascular events (p=0.008).Conclusion Adopting a new model of healthcare provides a means of delivering post-transplant patient care close to home without compromising patient survival and long-term clinical outcomes.