RT Journal Article SR Electronic T1 Hub-and-spoke model for thrombectomy service in UK NHS practice JF Clinical Medicine JO Clin Med FD Royal College of Physicians SP e26 OP e31 DO 10.7861/clinmed.2020-0579 VO 21 IS 1 A1 Liqun Zhang A1 Ayokunle Ogungbemi A1 Sarah Trippier A1 Brian Clarke A1 Usman Khan A1 Claire Hall A1 Qiuhong Ji A1 Andrew Clifton A1 Gillian Cluckie YR 2021 UL http://www.rcpjournals.org/content/21/1/e26.abstract AB Mechanical thrombectomy is a highly effective but time dependent treatment for acute ischaemic stroke due to large vessel occlusion. In the UK, the national clinical guidelines for stroke and National Institute for Health and Care Excellence guidance endorses thrombectomy as an acute stroke treatment, and NHS England commissioned thrombectomy services. However, there are no UK ‘real-world’ data to verify the efficacy of the hub-and-spoke model in thrombectomy. There are currently 24 tertiary neuroscience centres in the UK that can provide thrombectomy treatment and many of these operate only within working hours. This study is the first to demonstrate that a hub-and-spoke thrombectomy service in routine UK 24/7 clinical practice is as effective and safe as in the setting of randomised controlled clinical trials. However, there are 9.3% of patients accepted for transfer to the thrombectomy centre who did not proceed to thrombectomy, mostly due to delays. Fifty-three per cent of thrombectomy cases were performed outside of standard working hours when transfer delays were increased. A 24/7 thrombectomy service is needed to maximise the benefit to all suitable patients. Measures, including improving workflow and optimising work forces, are needed to minimise the delays and continue to improve the service.