PT - JOURNAL ARTICLE AU - Mujtaba Husain AU - Trudie Chalder TI - Medically unexplained symptoms: assessment and management AID - 10.7861/clinmed.2020-0947 DP - 2021 Jan 01 TA - Clinical Medicine PG - 13--18 VI - 21 IP - 1 4099 - http://www.rcpjournals.org/content/21/1/13.short 4100 - http://www.rcpjournals.org/content/21/1/13.full SO - Clin Med2021 Jan 01; 21 AB - Medically unexplained symptoms or persistent physical symptoms are common, real and are associated with significant distress, loss of functioning and high healthcare costs. History, examination and appropriate investigations are essential to make a diagnosis. Once the diagnosis has been made, exploring the impact of the symptoms helps us to tailor our advice to patients. This paper sets out a practical approach to taking a history, assessment and stepwise management principles.