RT Journal Article SR Electronic T1 Medically unexplained symptoms: assessment and management JF Clinical Medicine JO Clin Med FD Royal College of Physicians SP 13 OP 18 DO 10.7861/clinmed.2020-0947 VO 21 IS 1 A1 Mujtaba Husain A1 Trudie Chalder YR 2021 UL http://www.rcpjournals.org/content/21/1/13.abstract AB Medically unexplained symptoms or persistent physical symptoms are common, real and are associated with significant distress, loss of functioning and high healthcare costs. History, examination and appropriate investigations are essential to make a diagnosis. Once the diagnosis has been made, exploring the impact of the symptoms helps us to tailor our advice to patients. This paper sets out a practical approach to taking a history, assessment and stepwise management principles.