TY - JOUR T1 - If it ain’t broke don’t fix it: Lack of review of antimicrobials in ‘well’ patients – time for a CRP change JF - Future Healthcare Journal JO - Future Healthc J SP - e92 LP - e95 DO - 10.7861/fhj.2019-0042 VL - 8 IS - 1 AU - Amanda Hill AU - Eloise Hamon AU - Melanie Nana AU - Sian Price AU - Noel Craine AU - Brendan Healy Y1 - 2021/03/01 UR - http://www.rcpjournals.org/content/8/1/e92.abstract N2 - Introduction The rising prevalence of multi-resistant organisms threatens the efficacy of current antimicrobial treatments. Antibiotic stewardship is a key factor in slowing the development of resistance and must become part of a clinician’s regular practice. National guidance unanimously emphasises the importance of a 48-hour review of antimicrobial prescriptions. We assessed the compliance of antibiotic reviews across two sites in Wales.Method Two cycles of data were retrospectively collected across two teaching hospitals in Wales prior and following introduction of an antimicrobial alert sticker. A univariate odds ratio for 48-hour referral stratified by C-reactive protein (CRP) was calculated in a logistic regression model for the cycle one data.Results One-hundred and thirty-nine patients were included in the cycle 1 data across both sites. We identified that patients with a CRP ≤100 mg/L (a marker of less severe infection) were less likely to have their antibiotic prescription reviewed by 48 hours.Discussion Patients with CRP ≤100 mg/L were less likely to receive a 48-hour review of their antimicrobial prescription. Compliance with review improved following introduction of a simple alert measure. ER -