PT  - JOURNAL ARTICLE
AU  - Leticia Sanz-Canalejas
AU  - María del Carmen Polidura-Arruga
AU  - Miguel Yus-Fuertes
AU  - Manuela Jorquera-Moya
AU  - Nieves Vidart-Simón
AU  - Juan Arrazola-García
AU  - Natividad Gómez-Ruiz
TI  - Lesson of the month: Severe leukoencephalopathy by SARS-CoV-2
AID  - 10.7861/clinmed.2020-0940
DP  - 2021 Mar 01
TA  - Clinical Medicine
PG  - 155--157
VI  - 21
IP  - 2
4099  - http://www.rcpjournals.org/content/21/2/155.short
4100  - http://www.rcpjournals.org/content/21/2/155.full
SO  - Clin Med2021 Mar 01; 21
AB  - Neurological manifestations associated with SARS-CoV-2 infection as well as its pathogenesis are insufficiently explained. We present two cases of severe COVID-19 who required hospitalisation in the intensive care unit with persistently depressed mental status and severe leukoencephalopathy. We discuss the clinical and radiological findings and also propose the possible pathogenesis involved.