RT Journal Article SR Electronic T1 When common things aren't so common: A case report of hepatopulmonary syndrome JF Clinical Medicine JO Clin Med FD Royal College of Physicians SP 226 OP 227 DO 10.7861/clinmed.2021-0142 VO 21 IS 3 A1 Emma Keelan A1 Chris Ferguson A1 Rebecca Kerr YR 2021 UL http://www.rcpjournals.org/content/21/3/226.abstract AB A 60-year-old smoker with a history of liver cirrhosis and chronic obstructive pulmonary syndrome (COPD) presented with hypoxic respiratory failure. This was felt secondary to an exacerbation of COPD. Despite treatment, the patient required 10 L of oxygen to achieve saturations of 88% on ambulation. Interstitial lung disease, pulmonary emboli and pulmonary hypertension were excluded as potential aetiologies of hypoxia. Given the history of cirrhosis, hepatopulmonary syndrome was postulated. Contrast echocardiography suggested an extracardiac shunt; a technetium-99m macroaggregated albumin scan confirmed the diagnosis.