RT Journal Article SR Electronic T1 Lessons of the month 2: Ocular manifestations and complications of hepatitis C infection JF Clinical Medicine JO Clin Med FD Royal College of Physicians SP e417 OP e419 DO 10.7861/clinmed.2021-0320 VO 21 IS 4 A1 Sarah LW Fang A1 Livia Teo A1 Cheng Yi Loo A1 James W Li A1 Anindita Santosa YR 2021 UL http://www.rcpjournals.org/content/21/4/e417.abstract AB We present a case of a man with hepatitis C with acute visual loss in his left eye over a 3-day period. Initial evaluation suggested a possible idiopathic orbital inflammatory syndrome as underlying cause for his symptoms. Initial response to systemic glucocorticoids and antiviral treatment were encouraging with improvement in the patient's visual acuity. After a period of loss to follow up and discontinuation of treatment, the patient re-presented with visual loss in his left eye. Re-evaluation confirmed a diagnosis of marginal zone B-cell lymphoma. This case illustrates the importance of considering the various ocular manifestations of hepatitis C.