PT - JOURNAL ARTICLE AU - Alp AA Notghi AU - Joseph Atley AU - Mark Silva TI - Lessons of the month 1: Longitudinal extensive transverse myelitis following AstraZeneca COVID-19 vaccination AID - 10.7861/clinmed.2021-0470 DP - 2021 Sep 01 TA - Clinical Medicine PG - e535--e538 VI - 21 IP - 5 4099 - http://www.rcpjournals.org/content/21/5/e535.short 4100 - http://www.rcpjournals.org/content/21/5/e535.full SO - Clin Med2021 Sep 01; 21 AB - Longitudinal extensive transverse myelitis (LETM) is a rare but recognised complication of vaccination. We report the case of a 58-year-old man admitted to hospital 10 days after his first AstraZeneca COVID-19 vaccination with progressive neurological symptoms and signs, and investigations and imaging consistent with LETM.This case reviews the literature and the investigative process behind excluding other diagnoses given the patient’s background of pulmonary sarcoidosis. It is unique in being the first UK report of a case of LETM with a strong temporal link to COVID-19 vaccination.