RT Journal Article SR Electronic T1 Lessons of the month 1: Longitudinal extensive transverse myelitis following AstraZeneca COVID-19 vaccination JF Clinical Medicine JO Clin Med FD Royal College of Physicians SP e535 OP e538 DO 10.7861/clinmed.2021-0470 VO 21 IS 5 A1 Alp AA Notghi A1 Joseph Atley A1 Mark Silva YR 2021 UL http://www.rcpjournals.org/content/21/5/e535.abstract AB Longitudinal extensive transverse myelitis (LETM) is a rare but recognised complication of vaccination. We report the case of a 58-year-old man admitted to hospital 10 days after his first AstraZeneca COVID-19 vaccination with progressive neurological symptoms and signs, and investigations and imaging consistent with LETM.This case reviews the literature and the investigative process behind excluding other diagnoses given the patient’s background of pulmonary sarcoidosis. It is unique in being the first UK report of a case of LETM with a strong temporal link to COVID-19 vaccination.