RT Journal Article SR Electronic T1 Patient and public understanding of the concept of ‘personalised medicine’ in relation to cancer treatment: a systematic review JF Future Healthcare Journal JO Future Healthc J FD Royal College of Physicians SP e703 OP e708 DO 10.7861/fhj.2021-0063 VO 8 IS 3 A1 Jed Botham A1 Valerie Shilling A1 John Jones YR 2021 UL http://www.rcpjournals.org/content/8/3/e703.abstract AB Personalised medicine (PM) is becoming increasingly integrated into standard clinical practice for treating numerous diseases, including cancer. Implementing PM into healthcare systems will only be successful with the acceptance and input of both patients’ and public opinion. This review, therefore, aimed to identify both patients’ and public understanding, and perceived benefits and concerns of PM in cancer treatment. A literature search was conducted using MEDLINE, EMBASE, PsycINFO and CINAHL databases. The eligibility criteria specified that papers must explore the public or patients’ understanding of PM or pharmacogenomic (PGx) testing in relation to cancer treatment. Patients have a greater understanding of, and trust in, PM compared with members of the public, but often misunderstand how genomic testing in PM works. Key areas that can be targeted to inform future health literacy interventions include genetic literacy for the public and understanding of how PM testing and treatment works for patients.