PT  - JOURNAL ARTICLE
AU  - Min-Hui Tan
AU  - Seow-Yeing Yee
AU  - Rosnawati Yahya
TI  - Lessons of the month 2: A case of inappropriate drug–drug interaction in kidney transplant
AID  - 10.7861/clinmed.2021-0789
DP  - 2022 Mar 01
TA  - Clinical Medicine
PG  - 169--171
VI  - 22
IP  - 2
4099  - http://www.rcpjournals.org/content/22/2/169.short
4100  - http://www.rcpjournals.org/content/22/2/169.full
SO  - Clin Med2022 Mar 01; 22
AB  - Carbamazepine remains a first-line antiepileptic medication for the treatment of partial seizures. Despite its widespread use, carbamazepine has significant neurotoxicity and hypersensitivity reactions. We report a case of a patient post-kidney transplant who was on regular carbamazepine for childhood epilepsy and developed nystagmus, diplopia and a broad-base gait after receiving diltiazem. Understanding of the interaction between diltiazem and carbamazepine is necessary to prevent the neurotoxic effects.