PT  - JOURNAL ARTICLE
AU  - Lauren Hookham
AU  - Corinne Fisher
AU  - Jessica J Manson
AU  - Matt Morgan
AU  - Geraldine O'Hara
AU  - Phil Riley
AU  - Rachel S Tattersall
AU  - Anna L Goodman
TI  - Understanding the diagnosis and management of multisystem inflammatory syndrome in adults (MIS-A) in the UK: results of a national Delphi process
AID  - 10.7861/clinmed.2021-0700
DP  - 2022 May 01
TA  - Clinical Medicine
PG  - 266--270
VI  - 22
IP  - 3
4099  - http://www.rcpjournals.org/content/22/3/266.short
4100  - http://www.rcpjournals.org/content/22/3/266.full
SO  - Clin Med2022 May 01; 22
AB  - Infection with SARS-CoV-2 may trigger a delayed hyper-inflammatory illness in children called paediatric multisystem inflammatory syndrome temporally associated with COVID-19 (PIMS-TS). A similar syndrome is increasingly recognised in adults termed multisystem inflammatory syndrome in adults (MIS-A) and may present acutely to medical or surgical specialties with severe symptoms, such as acute abdominal pain or cardiogenic shock. No national guidelines exist in the UK for the management of MIS-A and there is limited evidence to guide treatment plans. We undertook a national Delphi process to elicit opinions from experts in hyperinflammation about the diagnosis and management of MIS-A with the dual aim of improving recognition and producing a management guideline. Colleagues in paediatrics successfully initiated a national consensus management document that facilitated regional multidisciplinary referral and follow-up pathways for children with PIMS-TS, and we propose a similar system be developed for adult patients across the UK. This would facilitate better recognition and treatment of MIS-A across the multiple specialties to which it may present as well as enable follow-up with specialty services post-discharge.