PT  - JOURNAL ARTICLE
AU  - Marco Vincenzo Lenti
AU  - Gabriele Croce
AU  - Alice Silvia Brera
AU  - Alessia Ballesio
AU  - Lucia Padovini
AU  - Giampiera Bertolino
AU  - Antonio Di Sabatino
AU  - Catherine Klersy
AU  - Gino Roberto Corazza
TI  - Rate and risk factors of in-hospital and early post-discharge mortality in patients admitted to an internal medicine ward
AID  - 10.7861/clinmed.2022-0176
DP  - 2023 Jan 01
TA  - Clinical Medicine
PG  - 16--23
VI  - 23
IP  - 1
4099  - http://www.rcpjournals.org/content/23/1/16.short
4100  - http://www.rcpjournals.org/content/23/1/16.full
SO  - Clin Med2023 Jan 01; 23
AB  - Background We sought to quantify in-hospital and early post-discharge mortality rates in hospitalised patients.Methods Consecutive adult patients admitted to an internal medicine ward were prospectively enrolled. The rates of in-hospital and 4-month post-discharge mortality and their possible associated sociodemographic and clinical factors (eg Cumulative Illness Rating Scale [CIRS], body mass index [BMI], polypharmacy, Barthel Index) were assessed.Results 1,451 patients (median age 80 years, IQR 69–86; 53% female) were included. Of these, 93 (6.4%) died in hospital, while 4-month post-discharge mortality was 15.9% (191/1,200). Age and high dependency were associated (p<0.01) with a higher risk of in-hospital (OR 1.04 and 2.15) and 4-month (HR 1.04 and 1.65) mortality, while malnutrition and length of stay were associated (p<0.01) with a higher risk of 4-month mortality (HR 2.13 and 1.59).Conclusions Several negative prognostic factors for early mortality were found. Interventions addressing dependency and malnutrition could potentially decrease early post-discharge mortality.