PT - JOURNAL ARTICLE AU - Samuel J Westall AU - Ei Thuzar Aung AU - Helmine Kejem AU - Christina Daousi AU - Sravan K Thondam TI - Management of pituitary incidentalomas AID - 10.7861/clinmed.2023-0020 DP - 2023 Mar 01 TA - Clinical Medicine PG - 129--134 VI - 23 IP - 2 4099 - http://www.rcpjournals.org/content/23/2/129.short 4100 - http://www.rcpjournals.org/content/23/2/129.full SO - Clin Med2023 Mar 01; 23 AB - Pituitary incidentalomas are common findings with increasing use of modern neuroradiological imaging undertaken for symptoms unrelated to pituitary disease. The prevalence of these lesions is ∼10% in autopsy studies and the incidence varies from 10% to 38% on magnetic resonance imaging in the published literature. They are almost always benign in nature and most are non-functioning (non-secreting) adenomas. Although many individuals are asymptomatic at diagnosis, some with functioning (secreting) pituitary adenomas or larger non-functioning adenomas have symptoms. All identified cases should have a thorough clinical and endocrinological evaluation to help with precise management, which depends on the size of the lesion, hormonal status (functioning versus non-functioning adenoma) and the presence of visual deficits resulting from optic nerve compression by the pituitary adenoma. Here, we provide an overview of the initial assessment and management of pituitary incidentalomas for clinicians not routinely involved in the management of pituitary disease.